The Spirit Molecule investigates dimethyltryptamine (DMT), an endogenous psychoactive compound, which exists in humans and numerous species of plants and animals. The documentary traces Dr. Rick Strassman’s government-sanctioned, human DMT research and its many trials, tribulations, and inconceivable realizations.

A closer examination of DMT’s effects through the lens of two traditionally opposed concepts, science and spirituality, The Spirit Molecule explores the connections between cutting-edge neuroscience, quantum physics, and human spirituality.